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VIDAZA was administered in a subcutaneous dose of 75 mg/m² everyday for 7 days each and every four weeks. The dose was elevated to a hundred mg/m² if no valuable impact was seen just after 2 cure cycles. The dose was diminished and/or delayed according to hematologic reaction or evidence of renal toxicity. Patients during the observation arm had been allowed by protocol to cross over to VIDAZA if they'd improves in bone marrow blasts, decreases in hemoglobin, raises in red mobile transfusion demands, or decreases in platelets, or if they essential a platelet transfusion or designed a scientific infection necessitating therapy with antibiotics. For functions of evaluating efficacy, the primary endpoint was response rate (as defined in Desk four).
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